whose lab has been experimenting with this new structure. Though technologies like LNPs have improved RNA therapeutics’ durability, they can’t bypass other challenges in drug delivery. Mitragotri says ...

Just as a chef perfects a dish by experimenting with flavors and textures, the researchers used an iterative process, testing variations to find the ideal structure ... its own, RNA is fragile ...

With PAN004, he explained, the company has developed an mRNA-LNP delivering an mRNA encoding a Tie2 activator selectively at the site where lung oedema occurs. Addressing challenges in RNA ...

The team unveiled its programmable LNP delivery platform in October 2023 and has continued to demonstrate the power of AI/ML to more safely and effectively deliver RNA therapies to specific ...