Researchers have developed lipid nanoparticles (LNPs) that cross the blood-brain barrier (BBB) and precisely target brain cells, a major step toward treating neurological diseases like Alzheimer’s.

This LNP 55 was encapsulated with VEGF mRNA and tested in two mouse models of pre-eclampsia ... without inducing adverse ...

LNP platform technology that enables delivery of a wide range of genetic cargos to organs and cells beyond the liver (Fig. 1). Conventional LNPs have four lipid components. To get LNPs beyond the ...

Alltrna, a Flagship Pioneering company unlocking transfer RNA (tRNA) biology and pioneering tRNA therapeutics to regulate the ...

LNPs are an ideal delivery ... LNP-based CRISPR-Cas9 candidate treatment for people with heterozygous familial hypercholesterolemia in clinical trials, which targets the PCSK9 gene in the liver.