Diagnosis. Activation of systemic lupus erythematosus with cerebritis following pegylated interferon therapy. Management. Intravenous fluid, intermittent oxygen, intravenous diphenylhydantoin ...

Recent insights reveal the potential role of interferon (IFN) signaling in the pathogenesis of OPLL, particularly the type I IFN pathway, which is known to play a role in innate immune responses ...

These heart cells rupture and leak DNA, which sparks a damaging immune response. This breakthrough challenges long-held ...

"Should an interferon alternative be introduced, or used to augment existing treatments?" Macrophage stimulation or activation can be initiated by a variety of different stimuli including beta ...

“It’s usually not linear.” To measure the downstream impact of having more receptors, the researchers exposed cells to interferons to activate the receptors, and found that the expression of infection ...

However, when the scientists removed VDAC2, tumor cells better received the calls from interferon-gamma produced by T cells, ...

High serum type I interferon (IFN) scores ... development of a standardized clinical test to measure IFN pathway activation as a biomarker of disease activity in patients with diffuse cutaneous ...