An international team of scientists including researchers from The Australian National University (ANU) have identified a ...

Scientists have identified a rare, mutated version of a protein called TNIP1 that causes a chronic autoimmune disease similar to Sjogren's Syndrome -- a condition that leads to extreme dryness of the ...

Mahin had a persistently elevated platelet count, which seemed detached from his liver condition, something we could not ...

Axatilimab is a humanized IgG4 monoclonal antibody that targets colony stimulating factor-1 receptors expressed on monocytes and macrophages.

The systemic disease of which AIP is a part has been called IgG4-related systemic diseases. AIP mimics pancreatic cancer and it is critically important to distinguish between the two diseases.

Researchers from Igyxos SA presented the preclinical profile of IGX-12, a humanized IgG4 antibody, in both female and male infertility models. BioWorld Science Conferences Genitourinary/sexual ...

The following is a summary of “Severe Eosinophilic Asthma or Eosinophilic Granulomatosis with Polyangitis: potential ...

The properties of the different IgG isotypes should be considered in developing therapeutic antibodies. To address this problem, antibody engineers introduced a serine-to-proline substitution that ...

an IgG4 monoclonal antibody that is an agonist of CD137, a key co-stimulatory receptor on immune cells. It also develops CTX-8371, a bispecific inhibitor that targets PD-1 and PD-L1 checkpoint ...

The company is developing LYT-100, which is under Phase 2 stage, to treat idiopathic pulmonary fibrosis (IPF); and LYT-200, a IgG4 monoclonal antibody, currently under Phase 1/2 stage, targeting ...

For more information about Avalo, please visit www.avalotx.com. About AVTX-009 AVTX-009 is a humanized monoclonal antibody ...