The decrease in CD4 cells during HIV infection seems to be driven by immune activation, which does not always correlate with viral load. Experienced clinicians are all too familiar with the ...

Our data demonstrates that among patients initiating therapy in RLS with (mainly) an NNRTI-based regimen, CD4 cell count recovery is impaired in the presence of on-going HIV-RNA replication over ...

the transcription factor interferon responsive factors (IRFs) are key elements in the production of type I and III interferons. A group of researchers in Italy looked into the relationship between ...

Most HIV-negative adults have between 500 and 1500 CD4 cells in a cubic millimeter of blood. Most people with HIV who have an undetectable viral load can reach the normal range and often it is only a ...

It’s important for all people with HIV to have regular blood tests. The two most important blood tests are for CD4 and viral load. CD4 and viral load test results give essential information about the ...

CD4-positive T cells are a subtype of lymphocyte. They are MHC class II-restricted and are important mediators of adaptive immunity. These cells are involved in both the induction and the ...