Interferon gamma (IFN-γ) is a cytokine that induces ... These interleukins’ stimulatory effects also result from intracellular signaling of transcription factors such as AP-1, JAK/STAT, and ...

In conclusion, this intriguing report builds on the work of many other groups by further unraveling MECP2 function in the ...

Without these genes, the mice exhibited defective signaling of a critical immune-modulating molecule called interferon-gamma, leading to enhanced activity of ILC2s and the associated inflammation that ...

We discovered that interferon gamma (IFNγ) promotes hematopoietic stem cell (HSC) division and myeloid differentiation in a mouse model of Mycobacterium avium infection (Nature 2010). Furthermore, ...

Along with defending against pathogens, the body's innate immune system helps to protect the stability of our genomes in ...

Let’s take a look at how differential signaling is different from single ended, and what that means for engineers and for users. Collectively, standards like TTL, CMOS, and LVTTL are known as ...

As noted above, stellate cell activation is the central event in hepatic fibrosis. Activation consists of 2 major phases: (1) initiation (also called apreinflammatory stage) and (2) perpetuation ...

Nov. 4, 2024 — Researchers have uncovered new targets that could be the key to effectively treating glioblastoma, a lethal type of brain cancer. These targets were identified through a screen ...

Wendy Clemens is Vice President of Early Development Oncology, Bristol Myers Squibb, leading a team of scientists that develop novel oncology therapeutics from pre-clinical stage through ...

We sell different types of products and services to both investment professionals and individual investors. These products and services are usually sold through license agreements or subscriptions ...

Members of the Proud Boys, key instigators in the Jan. 6, 2021, Capitol riot, are mobilizing in support of Donald Trump—and in some cases, making threats about the presidential election. While ...