Hox genes and their relatives are involved in several developmental processes in diverse animals, but when did they first arise? The genome sequence of the sponge Amphimedon queenslandica shows ...

In order for the pair of wings and the pair of halteres (as well as all other parts of the fly) to develop properly, the fly's suite of Hox genes must be expressed in a precise way and at precise ...

In particular, biologists have suspected that the insects' progression to six legs, and the evolution and modification of arthropod appendages in general, are driven by changes in Hox gene activity.

"There's a tight connection between the vertebrae and Hox genes," explains biophysicist Rory Cerbus, a member of Kyogo Kawaguchi's team. "We speculated that the genes, or something regulating them ...

“There’s a tight connection between the vertebrae and Hox genes,” explains biophysicist Rory Cerbus, a member of Kyogo Kawaguchi’s team. “We speculated that the genes, or something regulating them, is ...

MLL1 is rearranged in patients with acute leukaemia and leads to the deregulated expression of HOX genes, among other changes. MLL1 interacts with a wide variety of proteins, and four recent ...