To see if cryptic pockets were also present on other GTPases, Shokat and coworkers overlaid the sequence of these enzymes ...

Atomic resolution of the broad-spectrum antiviral drug cascade to facilitate the design of antiviral drugs ...

When people eat, they ingest the nucleic acids that reside in all living things. The compounds in these acids could inhibit ...

Innovative use of lipid nanoparticles to deliver immune agonists shows promise in activating anti-tumor immunity in ...

Certain nucleosides impede the replication of tumor cells as a step toward preventing cancer. When individuals consume food, ...

15 ) More accurately, it is the physiological precursor of nitric oxide (NO), a molecule that relaxes the muscles around blood vessels by cyclic guanosine monophosphate (cGMP) induction which causes ...

When people eat, they ingest the nucleic acids that reside in all living things. The compounds in these acids could inhibit the growth of cancer cells, according to findings published in PLOS ONE by ...

First, investigators studied an early step in the biochemical cascade triggered by nitric oxide—the metabolism of cyclic guanosine monophosphate (cGMP). They found that cGMP in spiny projection ...

These reactions increase the production of cyclic guanosine monophosphate, a compound that relaxes smooth muscles in the blood vessels. As a result, more blood can flow into the penis ...

As NO diffuses through the alveolar membrane, it reaches these smooth muscle cells, causing an increase in the levels of cyclic guanosine monophosphate that in turn sets off a chain of events ...

coli, these are called EF-Tu and EF-Ts), as well as guanosine triphosphate (GTP) as an energy source for the process. Upon binding of the tRNA-amino acid complex in the A site, GTP is cleaved to ...

V. (Nasdaq: PRQR) (ProQR), a company dedicated to changing lives through transformative RNA therapies based on its ...