The venture aims to advance MeiraGTx’s Parkinson’s gene therapy through Phase III trials with up to $430m in funding from ...
The Parkinson’s gene therapy, AAV-GAD, delivers the glutamic acid decarboxylase (GAD) gene into the subthalamic nucleus, a part of the brain key to motor control. It’s the same region targeted ...
With MeiraGTx eyeing up how to take the drug through phase 3 and onto commercialization, Hologen has stepped in. The ...
Shares in the Anglo-US biotech rose sharply after the announcement, which came off the back of new data showing that the AAV-GAD gene therapy met targets for safety and efficacy in the MGT-GAD-025 ...
(Nature Genetics) A high dose of the investigational gene therapy AAV-GAD, which delivers the glutamic acid decarboxylase (GAD) gene to the subthalamic nucleus to boost levels of GABA, was safe ...