Ferroptosis offers new strategies to combat treatment resistance in digestive tract cancers, enhancing the efficacy of ...

Researchers at Helmholtz Munich, in collaboration with colleagues at Tohoku University, have identified a specific redox protein as a critical regulator of ferroptosis - a form of regulated oxidative ...

Researchers at Helmholtz Munich and Tohoku University have discovered that PRDX6, a selenium carrier protein, plays a key ...

Ferroptosis represents a distinct cell death pathway regulated by iron metabolism, ROS production, and lipid peroxidation.

Ferroptosis represents a distinct cell death pathway regulated by iron metabolism, ROS production, and lipid peroxidation. The primary trigger for ferroptosis involves excessive accumulation of ...

Ferroptosis is a unique form of regulated ... D significantly increased the levels of reactive oxygen species (ROS) and lipid peroxidation in lung cancer cells. In xenograft mouse models, the ...

These include identifying the ultimate executors of ferroptosis post-lipid peroxidation ... accumulation of reactive oxygen species (ROS) and the peroxidation of polyunsaturated fatty acids ...