De Maria, R. et al. Functional expression of Fas and Fas ligand on human gut lamina propria T lymphocytes. A potential role for the acidic sphingomyelinase pathway in normal immunoregulation. J. Clin.

For example, it ignores the possible role of autocrine CD95/Fas activation, and possible effects of CD95L/FasL or the blocking antibodies on more distant targets such as circulating lymphocytes or ...

New in vivo evidence confirms that tumor-expressed Fas ligand impairs immune responses to cancer by inducing apoptosis of anti-tumor immune effector cells. A recent report demonstrated that murine ...