Overexpression of fibroblast growth factor receptor 3 (FGFR3) has been shown to drive oncogenesis in a subset of patients with multiple myeloma. However, epithelial cancers — such as bladder ...

Kidney failure and damage are common complications of multiple myeloma, a type of blood cancer. But there are several treatment options to help counteract kidney failure. Multiple myeloma is a ...

Genetic abnormalities alter the expression of adhesion molecules on myeloma cells, as well as responses to growth stimuli in the microenvironment. [108] In addition to therapy directed at MM cells ...

The stage of your myeloma tells your doctor about how it is affecting you and how it might develop. Doctors use the international staging system to stage myeloma. There are 3 stages: stage 1, stage 2 ...

A multiple myeloma diagnosis is a life event that can be overwhelming. Get trusted information for every step of your journey. Multiple myeloma can be tricky. That’s because it sometimes has no ...

In addition, 38 human myeloma cell lines, tonsil plasma cells, bone marrow PCs, normal plasmablasts, tonsil B cells, and peripheral blood B cells were also analyzed. Further genomic analysis of ...

A stem cell transplant can be a good treatment for multiple myeloma. A successful transplant gives someone with multiple myeloma new, healthy bone marrow. It replaces the bone marrow harmed by myeloma ...

Multiple myeloma is a rare type of cancer. It starts with the uncontrolled production of plasma cells. These are a type of white blood cell in the bone marrow. Healthy plasma cells make antibodies ...

Your GP might arrange: Blood tests also look for abnormal types of antibodies (immunoglobulins) called paraproteins. Myeloma makes paraproteins. These blood tests include: serum protein ...

“These compelling overall survival data support the clinical benefit ELREXFIO has already demonstrated and its potential to be a transformative treatment option for people with multiple myeloma ...