Recently, we reported that disruption of the TBX4-FGF10 epithelial-mesenchymal signaling in human lung organogenesis due to complex compound inheritance results in interstitial neonatal lung disorders ...
Moreover, thalidomide's binding to cereblon suppressed expression of chick genes encoding two growth factors important for limb patterning, Fgf8 and Fgf10 — although exactly how is unclear.