The transformation of healthy cells into invasive colorectal tumors is an extraordinarily complex process involving numerous ...

These phosphorylation reactions control the activity of many enzymes involved in intracellular signaling pathways. Specifically, the addition of phosphate groups causes a conformational change in ...

Life has evolved over billions of years, adapting to the changing environment. Similarly, enzymes—proteins that speed up ...

The cell can control a metabolic pathway by the presence or absence of a particular enzyme. The cell can also regulate the rate of reaction of key enzymes. The binding of the enzyme to its ...

New research offers unprecedented insight into how an enigmatic enzyme, known as CDK7, drives the cell cycle and cell proliferation.