Inactivation of the von Hippel–Lindau (VHL) tumour-suppressor gene is linked to the development of several different tumour types in humans, including tumours of the kidney, retina, central ...
The Von-Hippel Lindau (VHL) gene encodes for a tumor suppressor protein, pVHL, which is responsible for the regulation of a family cancer syndrome. Mutations in pVHL render the protein non-functional ...