Moreover, they also directly bind to RNA-binding proteins, which can be integrated into a complex mechanistic network. E2F1, an extensively studied transcription factor, mediates multiple malignant ...
Pancreatic ductal adenocarcinoma (PDAC) is a lethal cancer with a median survival of less than 6 months and a 5-year survival rate of only 10% (Siegel et al., 2020). Surveillance of high-risk ...
Background: A common missense variant of the CDKN2A gene (A148T) predisposes to malignant melanoma in Poland. An association between malignant melanoma and breast cancer has been reported in several ...
E2F1-associated purine synthesis pathway is a major component of the MET-DNA damage response network
Genes encoding these enzymes are regulated through E2F1, whose levels decrease upon METi in MET-driven cells and xenografts. Transient E2F1 overexpression prevented dNTPs depletion and the concomitant ...
Stephen E. and Catherine Pappas Center for Neuro-Oncology, Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts. *Corresponding Author: Julie J.
A biosignal is any signal in living beings that can be continually measured and monitored. The term biosignal is often used to refer to bioelectrical signals, but it may refer to both electrical and ...
*This calculation is an estimate only. We’ve estimated your taxes based on your provided ZIP code. Title, other fees, and incentives are not included. Monthly payment estimates are for ...
1 Department of Ophthalmology, The Second Affiliated Hospital of Kunming Medical University, Kunming, China 2 Department of Ophthalmology, Dali Bai Autonomous Prefecture People’s Hospital, Dali, China ...
Lung cancer (LC) is one of the malignancies with the highest incidence and mortality in the world, approximately 85% of which is non-small cell lung cancer (NSCLC). Circular RNAs (circRNAs) exert ...
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