In contrast, inserting heteroatoms such as nitrogen and/or oxygen leads to new analogues of cage-like 3D rings. “These new rings could potentially serve as a substitute for flat heteroaromatic rings ...

When tested in mice, the compound—named BBI-2779—shrank gastric tumors and prevented the cancer from developing resistance to ...

It was the first drug produced through recombinant DNA technology and among the first genetically engineered products to be available to consumers. Following the success of Humulin, recombinant DNA ...

The team explains how known mutations impact drug resistance and highlights new DNA changes that could be explored further. The research, published today (18 October) in Nature Genetics ...