When human CRP is ligand bound, it triggers activation of the complement ... immune system. CRP (so named because it reacts with the C-polysaccharide protein of Streptococcus pneumoniae, a common ...
Although most patients infected with K. pneumoniae are immunocompromised, they typically retain a functioning complement system, thus suggesting the potential utility of complement-enhancing ...
Catherine Hyams PhD thesis defined the role of the Streptococcus pneumoniae capsule on pneumococcal interactions with complement factors and phagocytes, demonstrating that resistance to complement ...
Her current special research interests are on microbial innate immune evasion and the role of complement system in inflammatory ... The pathogen that fascinates him most is Streptococcus pneumoniae.
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