3: initially 1–2 tabs every 4hrs as needed. #4: initially 1 tab every 4hrs as needed. Max 360mg codeine and 4g acetaminophen per 24hrs. Conversion from other opioids: see full labeling.

In its pure form, codeine is available as immediate-release oral tablets of 15 milligrams (mg ... mg every 4 to 6 hours for pain relief, with a maximum dose of 360 mg in 24 hours.

GI or GU obstruction. Ultra-rapid metabolizers of codeine (may experience overdose symptoms). Drug abusers. Elderly. Debilitated. Labor & delivery. Pregnancy (Cat.C). Nursing mothers: not recommended.