With a few exceptions, eukaryotic chromosomes have a single centromere that ensures their accurate segregation during mitosis. Chromosomes that lack centromeres segregate randomly during mitosis ...

The study provides significant insights into cucumber centromeres by identifying key centromeric satellite sequences and ...

At the heart of the kinetochore is a specialized nucleosome that contains centromere protein (CENP)-A, a histone H3 homologue. Several inner kinetochore components (cyan and purple ovals ...

Replicated chromosomes remain attached to each other by their central region: the centromere. As long as they remain attached to each other the two identical copies of the chromosome are known as ...

Aug. 9, 2024 — Gene therapy could potentially cure genetic diseases but it remains a challenge to package and deliver new genes to specific cells safely and effectively. Existing methods of ...

When two breaks occur, a ring chromosome can be formed. Isochromosomes are usually mirror image chromosomes that result from single breaks close to the centromere, thus eliminating the whole of a long ...

Expert Rev Mol Diagn. 2012;12(5):511-526. Qualitative end-point RT-PCR can be used for minimal residual disease (MRD) monitoring, [36] but has been largely overtaken by quantitative techniques ...

shows a typical CT scan of FA associated with systemic sclerosis and Figure 1B shows the coarser, less homogeneous reticular pattern associated with CFA. Biopsies taken from patients with ...

Barton, I.S., Ren, Z., Cribb, C.B., Pitzer, P.E., Baglivo, I., Martin, D.W., Wang, X., Roop, R.M. (2023) Brucella MucR acts as an H-NS-like protein to silence ...