Our data show that inflammasome function, through the NLRP3–ASC–caspase 1–GSDMD axis, in bone marrow stromal cells controls the rate of hematopoietic stem cell proliferation and thereby ...
The researchers added yet one more piece to this puzzle using caspase-11-deficient mice. In these animals, inflammasome ...
In addition to its CNS focus, Jupiter is evaluating opportunities in longevity and metabolic health. Emerging data suggests that JOTROL’s inhibition of NLRP3, when combined with GLP-1 treatments, ...
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