Building on previous research, the Johns Hopkins scientists sought to better understand the interaction of two components in the mitochondrial membrane: cardiolipin, a fatty compound, or lipid ...

The condition is caused by mutations in the TAFAZZIN gene, which is crucial for the proper metabolism of cardiolipin, a phospholipid that plays a vital role in mitochondrial function. Recent ...

Barth syndrome is caused by a mutation in the tafazzin gene, which results in reduced cardiolipin levels, a phospholipid that plays a major role in mitochondrial function. The disease is characterized ...