For the endpoint assay, the spheroids were stained with a mixture of the Hoechst nuclear stain and viability dyes Calcein AM and EtHD. The spheroids were then subjected to imaging and analysis for ...

Calcein AM is membrane-permeable and is converted ... This was the only viability assay used by Guo et al., but we feel it is not sufficiently reliable in this context—as amply demonstrated ...

Dr Samuel Jones from Birmingham's School of Chemistry led the research team that developed the FAIRY assay. He said: "On average, every four years a new virus is discovered that has pandemic ...

D cancer cell models, like tumoroids, are tools of great value for cancer research and drug development because they are highly representative of the structure and behavior of tumors. Manual 3D cell ...