Turning powerful gene-editing technologies into broadly useful therapies will require delivery vehicles at once more simple ...

The amazing rise of RNA to delivering precise gene editing and its potential to unlock life's biggest secrets is told in The ...

As part of these so-called CRISPR-Cas systems, a CRISPR ribonucleic acid (crRNA), which serves as a “guide RNA,” recognizes regions of a foreign genome, such as viral DNA. The CRISPR-associated (Cas) ...

Generating CRISPR/Cas9-mediated mutants in tomato (Solanum lycopersicum L.) involves screening shoots regenerated from ...

An innovative CRISPR-Cas12f-based activator system may hold significant ... Researchers conducted experiments using ...

Scientists first discovered CRISPR in bacteria defending themselves against viruses. In nature, a Cas9 protein pairs with an RNA guide molecule to seek out viral DNA and, when located, chop it up.

Breast cancer (BC) remains the most prevalent cancer among women worldwide, presenting significant challenges due to its high ...

CRISPR-Cas9 genome editing exploits the CRISPR-Cas system to modify a genome in a targeted manner. Guided by RNA, the Cas9 endonuclease breaks DNA at a target sequence. Imprecise repair of the ...

Young adult mice with a genetic form of progressive deafness can hear again after being treated with an experimental CRISPR gene therapy that its creators hope to eventually use in humans. In an ...

Their novel method, called PUMA, enables the detection of RNA with Cas12 nucleases, which naturally target DNA. PUMA promises a wide range of applications and high accuracy. CRISPR-Cas systems ...

CRISPR-Cas systems, defense systems in bacteria, have become a plentiful source of technologies for molecular diagnostics.