A research team has discovered a novel mechanism essential for initiating autophagy. The study highlights the role of ZDHHC13, an enzyme that palmitoylates ULK1, in triggering autophagy.
Autophagy is a natural regeneration process that occurs at a cellular level in the body, reducing the likelihood of contracting some diseases as well as prolonging lifespan. In 2016, Japanese ...
Autophagosome biogenesis is impaired in Rett syndrome, a complex neurodevelopmental disorder caused by loss of function ...
Concurrent Inhibition of The RAS Pathway and Autophagy As a Treatment Approach for Pancreatic Cancer
Pancreatic ductal adenocarcinoma (PDAC) is characterized clinically by poor survival and mechanistically by KRAS- and autophagy-dependent growth. We and others previously demonstrated that inhibition ...
Gen Charles "CQ" Brown Jr: History-making fighter pilot picked as new Joint Chiefs of Staff chairman
President Joe Biden announced on Thursday that Gen Charles Brown would be the new chairman of the Joint Chiefs of Staff President Joe Biden has named Gen Charles "CQ" Brown Jr to be the next ...
PMID: 33008892. Seervai RNH, Grimm SL, Jangid RK, Tripathi DN, Coarfa C, Walker CL. An actin-WHAMM interaction linking SETD2 and autophagy. Biochem Biophys Res Commun. 2020 Oct 6:S0006-291X(20)31766-6 ...
DIRAS3-Derived Peptide Inhibits Autophagy in Ovarian Cancer Cells by Binding to Beclin1 ... PMID: 18221523. Hyser JM, Zeng CQ, Beharry Z, et al. Epitope mapping and use of epitope-specific antisera to ...
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