BN-CD38 eradicates acute myeloid leukemia (AML) by inducing the expression of its own therapeutic target and by expanding and redirecting autologous T-cells against AML blasts and leukemia stem cells.

IFNβ-induced AML-cell cytotoxicity is enhanced with anti-CD38 antibody daratumumab. (A-C) AML cell lines (MV-411, n = 9 experiments and OCI-AML3, n = 7 experiments) and primary AML apheresis ...

On September 20, the FDA approved isatuximab plus bortezomib, lenalidomide, and dexamethasone in the first line for patients ...

An investment adviser will not be required to apply its AML/CFT program to its nonadvisory activities. In the adopting release, FinCEN explained that, by way of example, certain activities ...

CD38 is highly and uniformly expressed on the surface of ... including multiple myeloma, acute myeloid leukemia, certain types of lymphomas, as well as gastrointestinal and lung cancers. MM is the ...

The rule requires advisers to implement an AML/CFT program, file SARs and reports with respect to currency transactions with FinCEN, and comply with recordkeeping requirements. The rule also ...

Inecalcitol is a vitamin D receptor agonist currently in Phase II clinical trial in AML (acute myeloid leukemia). Inecalcitol increases the expression of CD38 at the surface of 5 multiple myeloma cell ...

Acute myeloid leukemia is one of the deadliest cancers. Leukemic stem cells responsible for the disease are highly resistant to treatment. A new editorial paper was published in Oncotarget's ...

A total of 20 patients were enrolled in the trial, with 14 having myeloid blast-phase CML, four with accelerated-phase CML, and two with Philadelphia chromosome-positive AML. Overall, 50% of ...

Our technical assistance in anti-money laundering/countering the financing of terrorism (AML/CFT) offers innovative avenues for fighting crime and addressing the intersections of IFF and ...

The patient, who was suffering from acute myeloid leukemia, received the transplant at Henry Ford Hospital in Detroit, Michigan. She is now "rapidly recovering," according to doctors. "We were ...

Sep. 30, 2024 — A study of more than 700 counties across multiple U.S. states found a link between childhood leukemia and levels of decaying radon gas, including those lower than the federal ...