Cyclin D, encoded by the CCND1 gene, has already given rise to a class of widely used breast cancer drugs known as CDK4/6 inhibitors. Compared with targeting cyclin D and CDK4/6, which are ...

The firm reported $845 million in Q2 revenue from oncology products gained in its acquisition of Seagen last year.

The researchers believe BRAF and NRAS mutations may be driving the differences in cell size by regulating levels of a protein known as CCND1 – which is involved in cell division, growth and ...

The authors have no relevant affiliations or financial involvement with any organization or entity with a financial interest in or financial conflict with the subject matter or materials discussed ...

Professors Richard Houlston, Gareth Morgan and their team showed that patients with a mutation in the CCND1 gene were 80 per cent more likely to develop a particular sub-type of myeloma, a blood ...

Distorted functions of dendritic cells (DCs) have been implicated in aberrant intestinal inflammation, but the underlying ...