This video introduces a theory-driven multivariate behavior genetics model: the independent pathway model. The independent pathway model, also called the biometric factor model, first creates ...

Overactivation of this pathway leads to deposits of the complement protein C3 in glomeruli, triggering inflammation and kidney damage. Fabhalta is an oral small molecule designed to bind to and ...

including up to 89% mean reduction of complement component 3 (C3), which led to reductions of 85% in AH50 and 100% in Wieslab AP, both markers of alternative pathway complement activity.