Preclinical data showed promise in both systemic sclerosis bleomycin-induced mouse models and in patient-derived skin fibroblasts treated with EYD-001. The Food and Drug Administration (FDA ...

Good afternoon, and welcome to the MannKind Corporation third quarter 2024 financial results earnings call. As a reminder, ...

Examples include doxorubicin and bleomycin,” says Dr Shaikh. These drugs block the action of enzymes called topoisomerases, which help manage the structure of DNA during cell division. “By inhibiting ...

Subsequent studies found the molecules improved fibrosis in a Bleomycin-induced mouse lung fibrosis model and were safe when given to mice in a 14-day dose range-finding experiment. The whole ...

Not all patients with deterioration in pulmonary function tests have a progressive disease: 30% of patients develop progressive lung disease and only 16% will develop severe lung fibrosis (defined ...

Bristol-Myers Squibb was founded in 1858 and has grown to be one of today's leading global pharmaceutical companies. For over 150 years, Bristol-Myers Squibb (BMS) has been committed to "discover ...

This valuable paper shows image correlation spectroscopy (ICS) as a new tool to analyze the clustering of proteins involved in DNA damage response (DDR). The solid evidence presented demonstrates that ...

Q3 2024 Earnings Conference Call November 7, 2024 4:30 PM ETCompany ParticipantsMichael Castagna - CEOChris Prentiss ...