These include: Busulfan. You might take busulfan (Busulfex, Myleran) or ruxolitinib (Jakafi) if hydroxyurea isn’t helpful or if it causes severe side effects. It can bring your blood cell counts ...

Busulfan, at a dose that was adjusted for each patient, was administered to attain a target area under the curve of 17,000 to 21,000 μmol×min per liter. Baseline characteristics of the patients ...

A new research paper titled "ABT199/venetoclax synergism with thiotepa enhances the cytotoxicity of fludarabine, cladribine and busulfan in AML cells" has been published in Oncotarget.

The conditioning agents were busulfan–cyclophosphamide in the ALD-102 study and busulfan–fludarabine in the ALD-104 study. The multiplicity of infection (the number of transducing viral ...

While the use of elivaldogene autotemcel (eli-cel; Skysona) gene therapy has demonstrated long-term efficacy in patients with ...

Sergio A. Giralt, MD, discusses what the most commonly used conditioning regimens for patients with myelodysplastic syndrome ...

Either hydroxyurea or busulfan as single agents can provide hematologic control in the majority of patients (> 75%) with chronic phase CML. [32] These hematologic "remissions" are characterized by ...

If I had a younger patient who had myelofibrosis, I'll often use full dose — myeloablative busulfan along with fludarabine. Recently, though, I have changed from FLU-MEL over to Bu-Flu (busulfan ...

Editas Medicine, Inc. ( NASDAQ: EDIT) Strategic Update Conference Call October 22, 2024 8:00 AM ET ...

There was also interim data from the phase 3 study in patients with CALD after myeloablative conditioning using busulfan and fludarabine, a different chemotherapy conditioning regimen than that ...

Williams and colleagues pointed out that the conditioning agents used in the ALD-102 study (busulfan-cyclophosphamide) could potentially reduce the risk of cancer compared with the agents used in ...