Alternatively, BAFF could have direct effects on many cell types, given that BAFF receptors have been found on macrophages, dendritic cells and T cells and that these receptors seem to be ...

BAFF-R = B-cell-activating factor receptor; BCMA = B-cell-maturation antigen; CTLA4 = cytotoxic T-lymphocyte antigen 4; LTβR = lymphotoxin-β receptor; LTβR-Ig = anti-lymphotoxin-β receptor ...

Mechanism: Povetacicept is a dual-target fusion protein that simultaneously blocks both APRIL and BAFF by acting as a decoy receptor. Clinical significance: The RAINIER trial demonstrated ...

BAFF and SDF-1α from PEPROTECH EC (London, UK); rh TNFα, APRIL, IGF-1, VEGF, neutralizing mouse monoclonal antibodies against IL-6 and against IL-6 receptor from R&D Systems (Minneapolis ...