People with a BRCA1 gene mutation, which increases breast and ovarian cancer risk, are also at increased risk of impaired ...

It is generally recognized that certain factors related to endogenous and exogenous estrogen contribute to the risk of breast, ovarian, and endometrial cancers in women in the general population.

First, those that cannot be easily modified: age at menarche, age at birth of first child, family history, genes like BRCA1. And second, those that are modifiable: exercise, body weight, alcohol ...

More and more studies show that men face risks of cancer from BRCA1 and BRCA2 genetic mutations that are most often associated with breast and ovarian cancers in women. According to a July 25 JAMA ...

A research team led by Professor Ying Wai Chan from the School of Biological Sciences at The University of Hong Kong (HKU) ...

Researchers at Edith Cowan University (ECU) are making progress in understanding why uveal melanoma, the deadliest form of ...

Genes, the molecular architects of our existence, play an important role in determining our susceptibility to cancer ... have well-established genetic connections. Mutations in the BRCA1 and BRCA2 ...

New research shows that men can carry mutations in the BRCA1 and BRCA2 genes that increase their risk of several cancers.

Sensitivity to ionizing radiation is compelling evidence that BRCA1-and BRCA2-deficient cells are defective in repair of DSBs. As discussed above, 2 separate pathways play major roles in DSB repair in ...

Technology, gene sequencing, and validated laboratory science play key roles in early disease detection and patient ... for ...

Several studies have been completed looking at the effect of BPO in women at high risk of developing ovarian cancer because of family history or because of being mutation carriers of either BRCA1 ...

reveal the crucial role of a protein named FANCM in promoting resistance to these drugs. PARP inhibitors have shown ...