a humanized anti-IL.6 receptor antibody, has been approved as a biological drug for the treatment of rheumatoid arthritis, Castleman's disease and systemic JIA, and is expected to be applicable to ...

Mice injected with anti-IL-6 receptor monoclonal antibodies at the time of immunization had reduced disease incidence and less-severe histology scores than their wild-type littermates. Furthermore ...

Antibodies that interfere with IL-6 function Tocilizumab is a monoclonal antibody directed against the IL-6 receptor that has established benefit in RA both with regards to clinical efficacy and ...

in the presence of isotype control antibody or anti-IL-17A mAb for 3 weeks. 4 Measurement of IL-6 production by IL-17A and inhibition by AIN457 using ELISA assays As described earlier, 30 OCs were ...