The AI-designed proteins could form the basis of a new generation of therapies for snakebites — which kill an estimated ...
Each year, snake bites kill upwards of 100,000 people and permanently disable hundreds of thousands more, according to ...
Researchers have used artificial intelligence (AI ... proteins that can block the deadly effects of snake venom. They used a protein-design program called RFdiffusion to design ‘mini-binder ...
To date, most such proteins are copies of those found in nature. For this new study, the researchers used an AI model to mimic the evolutionary process of a protein that never existed naturally.
“This streamlined approach significantly reduces reliance on detailed structural data, thus expanding the scope for sequence-based exploration of protein-ligand interactions.” The researchers — ...
It has been a few years since AI began successfully tackling the challenge of predicting the three-dimensional structure of proteins, complex molecules that are essential for all life. Next ...
Finding proteins known as “broadly neutralising binders”, which work against a broad range of snake toxins, is becoming more feasible because of the breakthrough in AI. Prof Baker’s Nobel ...