Lorraine is a cultural and historical region in Northeastern France, now located in the administrative region of Grand Est. Its name stems from the medieval kingdom of Lotharingia, which in turn was named after either Emperor Lothair I or King Lothair II. Lorraine, originally the southern or "upper" part of this kingdom, came to be ruled by the Holy Roman E…Lorraine is a cultural and historical region in Northeastern France, now located in the administrative region of Grand Est. Its name stems from the medieval kingdom of Lotharingia, which in turn was named after either Emperor Lothair I or King Lothair II. Lorraine, originally the southern or "upper" part of this kingdom, came to be ruled by the Holy Roman Empire as the Duchy of Lorraine before the Kingdom of France annexed it in 1766.