Wolf Lake is an 804-acre lake that straddles the Indiana and Illinois state line near Lake Michigan. It is smaller than it was prior to settlement by European colonizers because of infilling for development around the edges. Despite years of environmental damage caused by heavy industries, transportation infrastructure, urban runoff and filling of wetl…Wolf Lake is an 804-acre lake that straddles the Indiana and Illinois state line near Lake Michigan. It is smaller than it was prior to settlement by European colonizers because of infilling for development around the edges. Despite years of environmental damage caused by heavy industries, transportation infrastructure, urban runoff and filling of wetlands, it is one of the most important biological sites in the Chicago region.