Saintes is a commune and historic town in western France, in the Charente-Maritime department of which it is a sub-prefecture, in Nou…Saintes is a commune and historic town in western France, in the Charente-Maritime department of which it is a sub-prefecture, in Nouvelle-Aquitaine. Saintes is the second-largest city in Charente-Maritime, with 25,518 inhabitants in 2021. The city's immediate surroundings form the second-most populous metropolitan area in the department, with 56,598 inhabitants. While a majority of the surrounding landscape consists of fertile, productive fields, a significant minority of the region remains forested, its natural state.