The Penn Museum is an archaeology and anthropology museum at the University of Pennsylvania. It is located on Penn's campus in the University City neighborhood of Philadelphia, at the intersection of 33rd and South Streets. Housing over 1.3 million artifacts, the museum features one of the most comprehensive collections of Middle and Near-Easteā¦The Penn Museum is an archaeology and anthropology museum at the University of Pennsylvania. It is located on Penn's campus in the University City neighborhood of Philadelphia, at the intersection of 33rd and South Streets. Housing over 1.3 million artifacts, the museum features one of the most comprehensive collections of Middle and Near-Eastern art in the world.