Newberry is a city in Newberry County, South Carolina, United States, in the Piedmont 43 miles northwest of Columbia. The charter was adopt…Newberry is a city in Newberry County, South Carolina, United States, in the Piedmont 43 miles northwest of Columbia. The charter was adopted in 1894. The population was 10,277 at the 2010 census. It is the county seat of Newberry County; at one time it was called Newberry Courthouse.