Gabu is the largest city in eastern Guinea-Bissau, the second most populated city in Guinea-Bissau and capital of the Gabu Region. Fou…Gabu is the largest city in eastern Guinea-Bissau, the second most populated city in Guinea-Bissau and capital of the Gabu Region. Founded under the name Kansala, Gabu was the capital of the Kaabu Empire until its destruction in 1867. The Portuguese renamed the town Nova Lamego ie "New Lamego", after the Douro town of Lamego. It was renamed Gabu in honor of the pre-colonial empire after Guinea Bissau's independence.