Etobicoke is an administrative district and former city within Toronto, Ontario, Canada. Comprising the city's west end, Etobicoke is bordered on the south by Lake Ontario, on the east by the Humber River, on the west by Etobicoke Creek, the cities of Brampton, and Mississauga, the Toronto Pearson International Airport, and on the north by the city of Vaugha…Etobicoke is an administrative district and former city within Toronto, Ontario, Canada. Comprising the city's west end, Etobicoke is bordered on the south by Lake Ontario, on the east by the Humber River, on the west by Etobicoke Creek, the cities of Brampton, and Mississauga, the Toronto Pearson International Airport, and on the north by the city of Vaughan at Steeles Avenue West.