University of Arizona Biosphere 2 is an American Earth system science research facility located in Oracle, Arizona. Its mission is to serve as a center for research, outreach, teaching, and lifelong learning about Earth, its living systems, and its place in the universe. It is a 3.14-acre structure originally built to be an artificial, materially closed ecological system, …University of Arizona Biosphere 2 is an American Earth system science research facility located in Oracle, Arizona. Its mission is to serve as a center for research, outreach, teaching, and lifelong learning about Earth, its living systems, and its place in the universe. It is a 3.14-acre structure originally built to be an artificial, materially closed ecological system, or vivarium. It remains the largest closed ecological system ever created.