COSI, officially the Center of Science and Industry, is a science museum and research center in Columbus, Ohio. COSI was opened to the public on 29 March 1964 and remained there for 35 years. In 1999, COSI was moved to a 320,000-square-foot facility, designed by Japanese architect Arata Isozaki along a bend in the Scioto River in the Franklinton neig…COSI, officially the Center of Science and Industry, is a science museum and research center in Columbus, Ohio. COSI was opened to the public on 29 March 1964 and remained there for 35 years. In 1999, COSI was moved to a 320,000-square-foot facility, designed by Japanese architect Arata Isozaki along a bend in the Scioto River in the Franklinton neighborhood. COSI features more than 300 interactive exhibits throughout themed exhibition areas.