Annecy is the prefecture and largest city of the Haute-Savoie department in the Auvergne-Rhône-Alpes region of Southeastern France. It lies o…Annecy is the prefecture and largest city of the Haute-Savoie department in the Auvergne-Rhône-Alpes region of Southeastern France. It lies on the northern tip of Lake Annecy, 35 kilometres south of Geneva, Switzerland.