FGF10 - Wikipedia
WEBFibroblast growth factor 10 is a paracrine signaling molecule seen first in the limb bud and organogenesis development. FGF10 starts the developing of limbs and its involved in the branching of morphogenesis in multiple organs such as …
FGF10 Gene - GeneCards | FGF10 Protein | FGF10 Antibody
WEBAug 6, 2024 · FGF10 (Fibroblast Growth Factor 10) is a Protein Coding gene. Diseases associated with FGF10 include Aplasia Of Lacrimal And Salivary Glands and Lacrimoauriculodentodigital Syndrome 3. Among its related pathways are Apoptotic Pathways in Synovial Fibroblasts and Downstream signaling of activated FGFR2.
Fgf10: a paracrine-signaling molecule in development, disease, …
WEBFgf10 is an epithelial-mesenchymal signaling molecule. Fgf10 knockout mice show severe phenotypes with complete truncation of the fore- and hindlimbs and die shortly after birth due to impaired lung development, indicating that Fgf10 serves as an essential regulator of lung and limb formation.
FGF/FGFR signaling in health and disease - Nature
WEBSep 2, 2020 · Growing evidences suggest that the fibroblast growth factor/FGF receptor (FGF/FGFR) signaling has crucial roles in a multitude of processes during embryonic development and adult...
Fgf10 Signaling in Lung Development, Homeostasis, Disease, and Repair ...
WEBSep 25, 2018 · Fibroblast growth factor 10 (Fgf10) located in the lung mesenchyme is essential to regulate epithelial proliferation and lineage commitment during embryonic development and post-natal life, and to drive epithelial regeneration after injury.
Regulation of FGF10 Signaling in Development and Disease
WEBOct 23, 2018 · Fibroblast Growth Factor 10 (FGF10) is a multifunctional mesenchymal-epithelial signaling growth factor, which is essential for multi-organ development and tissue homeostasis in adults. Furthermore, FGF10 deregulation has been associated with human genetic disorders and certain forms of cancer.
FGF10 gene - MedlinePlus
WEBThe FGF10 gene provides instructions for making a protein called fibroblast growth factor 10 (FGF10). Learn about this gene and related health conditions.
FGF10 Signaling in Heart Development, Homeostasis, Disease and …
WEBNov 28, 2018 · Among the 22 human/mouse FGFs, the secreted FGF10 ligand through the binding of its specific receptors (FGFR1b and FGFR2b) and subsequent activation of downstream signaling is known to play essential role …
The FGF family: biology, pathophysiology and therapy - Nature
WEBHuman Genome Science explored recombinant FGF10 (repifermin) as a treatment option for ulcerative colitis and mucositis, but its development was terminated in 2004 after it failed in several ...
Fibroblast growth factor 10 - ScienceDirect
WEBNov 25, 2023 · Fibroblast growth factor 10 (FGF10) is a major morphoregulatory factor that plays essential signaling roles during vertebrate multiorgan development and homeostasis.
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